# US 7,408,080 B2 · Process for ammoximation of carbonyl compounds > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 7,408,080 B2 - Document ID: US7408080B2 - Status: Granted - Kind: B2 - Application number: 10/448,282 - Filed: 2003-05-30 - Published: 2005-09-29 - Granted: 2008-08-05 - Earliest claimed: 2002-05-31 - Assignees: China Petroleum & Chemical Corporation; Research Institute of Petroleum Processing, Sinopec - Inventors: Wei Wu; Bin Sun; Yongxiang Li; Shibiao Cheng; Enquan Wang; Shuzhong Zhang - Web page: https://patentgrep.com/patent/US7408080B2 ## CPC - C07C 251/48: with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring - C07C 249/04: of oximes - C07C 251/38: to carbon atoms of a saturated carbon skeleton - C07C 251/42: with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a ring other than a six-membered aromatic ring - C07C 2601/08: the ring being saturated - C07C 2601/14: The ring being saturated - C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS ## Abstract The present invention discloses a process for the ammoximation of carbonyl compounds, wherein a reaction in a liquid reaction system comprising a carbonyl compound, ammonia and hydrogen peroxide is carried out in the presence of a sillicon-containing catalyst, characterized in that a liquid silicon-containing assistant is added to the reaction system so that the silicon concentration in the system reaches a range of between 0.1 and 10000 ppm. In the process according to the present invention, the deactivation of catalyst due to dissolution of silicon in the catalyst can be reduced, thus lifetime of the catalyst extended and the stable operation time elongated. ## Claims ### Claim 1 A process for the ammoximation of carbonyl compounds, wherein a reaction in a liquid reaction system comprising a carbonyl compound, ammonia and hydrogen peroxide is carried out in the presence of a sillicon-containing catalyst, characterized in that a liquid sillicon-containing assistant is added to the reaction system so that the silicon concentration in the system reaches a range of between 0.1 and 10000 ppm. ### Claim 2 (depends on 1) The process according to claim 1, characterized in that said carbonyl compound is one selected from the group consisting of cyclohexanone, acetone, butanone, cyclopentanone, acetophenone, p-hydroxyacetophenone, cyclododeconone, furfural, benzaldehyde and p-methylbenzaldehyde. ### Claim 3 (depends on 1) The process according to claim 1, characterized in that said sillicon-containing catalyst is selected from the group consisting of a crystalline silica or a metal-dispersed silica catalyst. ### Claim 4 (depends on 3) The process according to claim 3, characterized in that said crystalline silica is titanium-containing crystalline silica. ### Claim 5 (depends on 4) The process according to claim 4, characterized in that said titanium-containing crystalline silica is one selected from the group consisting of TS-1, TS-2, Ti-ZSM-5, Ti-ZSM-12, Ti-ZSM-48, Ti-β, Ti-MCM-41 and Ti-MOR. ### Claim 6 (depends on 1) The process according to claim 1, characterized in that said sillicon-containing assistant is selected from the group consisting of inorganic silicon-containing substances or organic sillicon-containing substances. ### Claim 7 (depends on 6) The process according to claim 6, characterized in that said inorganic silicon-containing substance is selected from the group consisting of silica and silicates. ### Claim 8 (depends on 7) The process according to claim 7, characterized in that said silicate is selected from the group consisting of sodium silicate, potassium silicate and aluminum silicate. ### Claim 9 (depends on 6) The process according to claim 6, characterized in that said organic sillicon-containing substance is selected from the group consisting of silicate esters and silanes. ### Claim 10 (depends on 9) The process according to claim 9, characterized in that said silicate ester is ethyl silicate. ### Claim 11 (depends on 1) The process according to claim 1, characterized in that said liquid sillicon-containing assistant is added in an amount sufficient to make the silicon concentration in the reacting solution reach the equilibrium dissolution concentration of silicon in the solution. ### Claim 12 (depends on 1) The process according to claim 1, characterized in that said liquid sillicon-containing assistant is added continuously or in batch. ### Claim 13 (depends on 12) The process according to claim 12, characterized in that said liquid sillicon-containing assistant is added continuously. ### Claim 14 (depends on 1) The process according to claim 1, characterized in that said liquid silicon-containing assistant is silica sol or a silicon-containing solution.