# US 7,407,497 B2 · System for connecting a compatibility liner with a source of perishable therapeutic > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 7,407,497 B2 - Document ID: US7407497B2 - Status: Granted - Kind: B2 - Application number: 11/433,584 - Filed: 2006-05-15 - Published: 2006-09-14 - Granted: 2008-08-05 - Earliest claimed: 2001-01-12 - Assignees: Boston Scientific Scimed, Inc. - Inventors: Justin M. Crank; Timothy A. Ostroot - Web page: https://patentgrep.com/patent/US7407497B2 ## CPC - A61M 39/12: for joining a flexible tube to a rigid attachment - A61M 5/142: Pressure infusion, e.g. using pumps - A61M 25/0097: {characterised by the hub (tube connectors or tube couplings A61M39/10)} - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A system for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a hollow hub having a first end and a second end is provided. The first end of the hollow hub, which contains a bond port, is in fluid communication with the second end. The second end of the hollow hub may contain a docking groove that is sized to couple a reservoir to it. The system also includes an inner hypo-tube having a proximal tip and an inner lumen. This inner lumen is lined with a therapeutic compatible lining and is in fluid communication with the second end of the hub through the proximal tip of the inner hypo-tube. The inner lining and the proximal tip in this system are configured to shield therapeutic ejected from the reservoir from contacting materials that can diminish the integrity of the therapeutic. ## Claims ### Claim 1 A system for delivery of therapeutic agent from a source of therapeutic agent through a lumen, the system adapted for connection to the source, the system comprising: a hub having a proximal end and a distal end, the proximal end adapted to be connected into fluid communication with the source of therapeutic agent, wherein the hub has a constriction between its proximal end and its distal end; a delivery tube having a lumen, the delivery tube having a proximal end secured within the distal end of the hub and a distal end remote from the hub; and a tubular lining extending within the lumen of the delivery tube, the tubular lining compatible with the therapeutic agent; wherein the system further comprises a collar attached to the proximal end of the delivery tube, the collar being secured within the hub between the proximal end of the hub and the distal end of the hub, wherein the collar causes therapeutic agent delivered from the source and present within the proximal end of the hub to flow into the tubular lining, the collar and tubular lining configured to shield therapeutic agent from contacting materials that are not compatible with the therapeutic agent as the therapeutic agent enters the delivery tube. ### Claim 2 (depends on 1) The system of claim 1, wherein the collar is secured within the hub between the proximal end of the hub and the distal end of the hub by a friction fit. ### Claim 3 (depends on 1) The system of claim 1, wherein the collar is secured within the hub between the proximal end of the hub and the distal end of the hub by a press fit. ### Claim 4 (depends on 1) The system of claim 1, wherein the collar is formed of a material that causes the collar to shrink upon heating, and wherein the collar is secured within the hub between the proximal end of the hub and the distal end of the hub by heating the collar, inserting the collar into an area where it is to be secured, and allowing the collar to cool and thereby expand and be secured in place. ### Claim 5 (depends on 1) The system of claim 1, wherein the collar is secured at the constriction between the proximal end of the hub and the distal end of the hub by a friction fit. ### Claim 6 (depends on 1) The system of claim 1, wherein the collar is secured at the constriction between the proximal end of the hub and the distal end of the hub by a press fit. ### Claim 7 (depends on 1) The system of claim 1, wherein the collar is formed of a material that causes the collar to shrink upon heating, and wherein the collar is secured at the constriction between the proximal end of the hub and the distal end of the hub by heating the collar, inserting the collar into the constriction where it is to be secured, and allowing the collar to cool and thereby expand and be secured in place. ### Claim 8 (depends on 1) The system of claim 1, wherein the proximal end of the delivery tube is secured within the distal end of the hub by an adhesive material. ### Claim 9 (depends on 8) The system of claim 8, wherein the hub has at least one bond port to allow adhesive material to be injected into the hub. ### Claim 10 (depends on 1) The system of claim 1, wherein the collar is formed of a material compatible with the therapeutic agent. ### Claim 11 (depends on 1) The system of claim 1, wherein the tubular lining extends through the collar. ### Claim 12 (depends on 1) The system of claim 1, wherein the proximal end of the hub comprises a docking groove for connection of the hub to the source of therapeutic agent. ### Claim 13 A system for delivery of therapeutic agent from a source of therapeutic agent through a lumen, the system adapted for connection to the source, the system comprising: a hub having a proximal end and a distal end, the proximal end adapted to be connected into fluid communication with the source of therapeutic agent, wherein the hub has a constriction between its proximal end and its distal end; a delivery tube having a lumen, the delivery tube having a proximal end secured within the distal end of the hub and a distal end remote from the hub; and a tubular lining extending within the lumen of the delivery tube and through the constriction in the hub, the tubular lining compatible with the therapeutic agent; wherein the tubular lining has a flared end at its proximal end, the flared end being secured within the proximal end of the hub, the tubular lining extending from the proximal end of the hub into the delivery tube in the distal end of the hub, the lining configured to shield therapeutic agent delivered from the source and present within the proximal end of the hub from contacting materials that are not compatible with the therapeutic agent as the therapeutic agent enters the delivery tube. ### Claim 14 (depends on 13) The system of claim 13, wherein the flared end of the tubular lining is secured to an inner surface of the proximal end of the hub by an adhesive. ### Claim 15 (depends on 13) The system of claim 13, wherein the proximal end of the delivery tube is secured within the distal end of the hub by an adhesive material. ### Claim 16 (depends on 15) The system of claim 15, wherein the hub has at least one bond port to allow adhesive material to be injected into the hub. ### Claim 17 (depends on 13) The system of claim 13, wherein the proximal end of the hub comprises a docking groove for connection of the hub to the source of therapeutic agent.