System microscope

An optical microscope system comprising:

• a specimen mounting part which is supported above a reference surface by a plurality of support members, and which mounts a specimen;
• an inverted microscope, which is provided on the reference surface below the specimen mounting part independently of the plurality of support members, and which includes a first illumination path which radiates first optical illumination light from under the specimen mounting part, and an observation optical path which acquires detection light emitted from the specimen to which the first optical illumination light is radiated to observe the specimen from thereunder;
• a microscope with upright frame, which is provided on the specimen mounting part, and which includes a second illumination path which radiates second optical illumination light from above the specimen mounting part, and an observation optical path which acquires detection light emitted from the specimen to which the second optical illumination light is radiated to observe the specimen from thereabove;
• and
• a driving unit which integrally moves at least an entire one of the inverted microscope, including the first illumination path, and the microscope with upright frame, including the second illumination path, relative to the specimen mounting part, in a plane perpendicular to the observation optical path of the inverted microscope or the microscope with upright frame;
• wherein the inverted microscope and the microscope with upright frame observe different positions of the specimen simultaneously.