Back to results
US 7,405,199 B2Granted
Cross-linked glycopeptide-cephalosporin antibiotics
AssigneeTheravance, Inc.
InventorsDaniel Marquess, Martin S. Linsell, Paul Fatheree, Michael R. Leadbetter
Life of this patent
Estimating the term…
Abstract
This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
Claims6
A compound of the formula:
- or a salt thereof, wherein
- R4 is hydrogen or C1-6 alkyl;
- R5 is hydrogen or C1-6 alkyl;
- R6 is —CH2CH2—O—CH2CH2—
- R7 is hydrogen or C1-6 alkyl;
- one of R9 and R10 is hydroxy and the other is hydrogen;
- R11 and R12 are independently hydrogen or methyl;
- R13 is hydrogen or a group of formula (i):
- and
- X1 and X2 are independently hydrogen or chloro.
7 more elements
A compound of the formula:
- or a salt thereof.
Dependencies are inferred from the claim text.