Method for diagnosing inflammatory diseases and infections by the determination of LASP-1 immunoreactivity
AssigneeB.R.A.H.M.S GmbH
InventorsAndreas Bergmann, Christina Fischer-Schulz, Joachim Struck
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AssigneeB.R.A.H.M.S GmbH
InventorsAndreas Bergmann, Christina Fischer-Schulz, Joachim Struck
Estimating the term…
Method for early diagnosis and diagnosis, for prognosis and assessment of the severity and for therapy-accompanying monitoring of inflammatory diseases and infections, in particular sepsis-like systemic infections and Alzheimer's disease, in which the presence and/or amount of the protein LASP-1 (SEQ ID NO:1) or of the protein LAP-1 (SEQ ID NO:16) or of an immunoreactive fragment of one of these proteins in free and/or protein-bound form is determined, preferably as immunoreactivity, in a biological fluid, or optionally a tissue sample, of a patient, and conclusions are drawn with respect to the presence, the expected course, the severity or the success of a therapy of the inflammatory disease or of the infection from the presence and/or amount of the proteins determined.
A method for confirming a clinical diagnosis of a sepsis in a patient suspected of having sepsis, the method comprising:
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