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US 7,404,970 B2Granted
Pain relief composition, method to form same, and method to use same
AssigneeKonec, Inc.
InventorsGeorge R. Krsek, Enrique E. Durazo
Life of this patent
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Abstract
An oral dosage form which includes a bi-layer tablet consisting of an Actives Granulation layer and an Osmagen Granulation layer is disclosed. An encapsulant is disposed over that bi-layer tablet. The encapsulated bi-layer tablet includes an orally therapeutically effective dose of oxycodone in combination with dextromethorphan, where the weight ratio of oxycodone to dextromethorphan is 1:5. The oral dosage form does not include an opioid antagonist.
Claims5
An oral dosage form, comprising:
- a bi-layer tablet consisting of a first layer having a first surface and an opposing second surface and a second layer having a first surface and an opposing second surface, wherein said second surface of said first layer physically contacts said first surface of said second layer;
- an encapsulant disposed over said bi-layer tablet;
- wherein said first layer comprises an orally therapeutically effective dose of oxycodone HC1 in combination with dextromethorphan HBr, wherein the ratio of oxycodone HC1 to dextromethorphan HBr is 1:5 by weight;
- wherein said second layer comprises carboxy methyl cellulose, sodium chloride, and iron oxide;
- wherein said oral dosage form is formed to include an aperture extending through said encapsulant and into said first layer;
- and wherein said oral dosage form does not include an opioid antagonist.
3 more elements
Dependencies are inferred from the claim text.