Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels
AssigneeYeda Research and Development Co. Ltd.
InventorVivian I. Teichberg
Life of this patent
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Abstract
A method of reducing extracellular brain glutamate levels. The method comprises administering to a subject in need thereof a therapeutically effective amount of an agent capable of reducing blood glutamate levels thereby reducing extracellular brain glutamate levels.
Claims17
A method of reducing extracellular brain glutamate levels in a subject in need thereof, the method comprising intravenously administering to the subject a therapeutically effective amount of a glutamate modifying enzyme, thereby enhancing brain to blood glutamate efflux, thereby reducing extracellular brain glutamate levels.
A method of reducing extracellular brain glutamate levels, the method comprising intravenously administering to a subject in need thereof a therapeutically effective amount of a glutamate modifying enzyme and a co-factor thereof, thereby enhancing brain to blood glutamate efflux, thereby reducing extracellular brain glutamate levels.
Dependencies are inferred from the claim text.