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US 7,404,893 B2Granted
Chromatography cartridge and method for manufacturing a chromatography cartridge
AssigneeVarian, Inc.
InventorNicholas DeMarco
Life of this patent
Estimating the term…
Abstract
A chromatography cartridge. In some embodiments, the chromatography cartridge can include a tubular housing defining a longitudinal axis and including a relatively non-laser-writable first portion, and a relatively laser-writable second portion. The relatively laser-writable second portion can be positioned substantially parallel to the longitudinal axis and can define at least a portion of an outer surface of the tubular housing to allow data to be printed on the outer surface of the tubular housing with a laser.
Claims26
A chromatography cartridge comprising:
- a tubular housing having a first wall thickness, the tubular housing including a first open end, a second open end, and an inner volume defined between the first open end and the second open end;
- a first portion of the tubular housing formed of a first material, and
- a second portion of the tubular housing formed of a second material, the second portion defining a stripe on an outer surface of the tubular housing, the stripe extending substantially the length of the tubular housing and having a second wall thickness less than the first wall thickness;
- a plug including an annular groove adapted to receive one of the first open end and the second open end, a first portion of the plug positioned through the open end and into the inner volume and having an outer circumferential surface, a substantial portion of the outer circumferential surface having a length greater than the first wall thickness of the tubular housing and being fused to an inner surface of the tubular housing, and a second portion of the plug positioned outside the inner volume and extending toward the opposite open end, the second portion of the first plug extending along and overlapping a portion of an outer surface of the tubular housing, the plug including an aperture in fluid communication with the inner volume, and a protruding extension through which the aperture extends;
- a first frit positioned in the inner volume of the tubular housing, the first frit having a first surface oriented substantially parallel to a lateral surface of the first portion of the plug, the first surface of the first frit being in contact with the lateral surface of the first portion of the plug;
- a second frit positioned in the inner volume of the tubular housing and adjacent the second open end;
- and
- a chromatography medium positioned between the first frit and the second frit.
5 more elements
A chromatography cartridge comprising:
- a tube defining a longitudinal axis and including
- an inner volume,
- a first open end and a second open end,
- a relatively translucent first portion, and
- a relatively opaque second portion, the relatively opaque second portion positioned substantially parallel to the longitudinal axis and being visible from the exterior of the tube;
- a plug including an annular groove adapted to receive one of the first open end and the second open end, a first portion of the plug positioned through the open end and into the inner volume and having an outer circumferential surface, a substantial portion of the outer circumferential surface having a length greater than the first wall thickness of the tubular housing and being fused to an inner surface of the tubular housing, and a second portion of the plug positioned outside the inner volume and extending toward the opposite open end, the second portion of the first plug extending along and overlapping a portion of an outer surface of the tubular housing, the plug including an aperture in fluid communication with the inner volume, and a protruding extension through which the aperture extends;
- a first frit positioned in the inner volume of the tubular housing, the first frit having a first surface oriented substantially parallel to a lateral surface of the first portion of the plug, the first surface of the first frit being in contact with the lateral surface of the first portion of the plug;
- a second frit positioned in the inner volume of the tubular housing and adjacent the second open end;
- and
- a chromatography medium positioned between the first frit and the second frit.
7 more elements
A chromatography cartridge comprising:
- a tubular housing defining a longitudinal axis and including
- an inner volume, and
- an open end,
- a relatively non-laser-writable first portion, and
- a relatively laser-writable second portion, the relatively laser-writable second portion being positioned substantially parallel to the longitudinal axis and defining at least a portion of an outer surface of the tubular housing to allow data to be printed on the outer surface of the housing with a laser;
- a plug including an annular groove adapted to receive the open end, a first portion of the plug positioned through the open end and into the inner volume and having an outer circumferential surface, a substantial portion of the outer circumferential surface having a length greater than a wall thickness of the tubular housing and being fused to an inner surface of the tubular housing, and a second portion of the plug positioned outside the inner volume and extending toward an opposite open end, the second portion of the first plug extending along and overlapping a portion of the outer surface of the tubular housing, the plug including an aperture in fluid communication with the inner volume, and a protruding extension through which the aperture extends;
- a first frit positioned in the inner volume of the tubular housing, the first frit having a first surface oriented substantially parallel to a lateral surface of the first portion of the plug, the first surface of the first frit being in contact with the lateral surface of the first portion of the plug;
- a second frit positioned in the inner volume of the tubular housing and adjacent the second open end;
- and
- a chromatography medium positioned between the first frit and the second frit.
7 more elements
Dependencies are inferred from the claim text.