Benzene compounds

A compound of formula (1A-IV), or a pharmaceutically acceptable salt thereof:

• wherein ring A represents a benzene ring which is substituted with R5 and (R6)n, or an imidazole ring which is substituted with R5 and (R6)n;
• B represents formula (ix):
• wherein B is attached para to the NR1R2 substituent on the phenyl ring, and each of R12, R13, R14, and R15 represents a hydrogen atom, an unsubstituted alkyl group with 1 to 12 carbon atoms, an unsubstituted phenyl group or a cyclic alkyl group with 3 to 12 carbon atoms, or R12 and R13 may join together to make a five- or six-membered) ring;
• D represents a nitro group, or an amino group substituted with R3 and R4;
• each of R1, R2, R3, and R4 represents a) a hydrogen atom, b) an unsubstituted alkyl group with 1 to 12 carbon atoms, c) a substituted alkyl group with 1 to 12 carbon atoms which is substituted with 1) a phenyl group which may have further one or more substituents, 2) a naphthyl group, 3) a cyclic alkyl aroup with 3 to 6 carbon atoms, 4) a thienyl group, 5) a furyl group, 6) a thiazolyl group, 7) an isothiazolyl group, 8) an imidazolyl group, 9) a pyridyl group, or 10) a benzyloxy group, d) an unsubstituted alkenyl group with 2 to 12 carbon atoms, e) a substituted alkenyl group with 2 to 12 carbon atom which is substituted with phenyl group, f) an unsubstituted alkynyl group with 2 to 12 carbon atoms, g) a substituted alkynyl group with 2 to 12 carbon atom which is substituted with phenyl group, h) a phenyl group which may have further one or more substituents, i) an unsubstituted naphthyl group, j) an substituted acyl group with 1 to 18 carbon atoms, k) an unsubstituted pyridyl group, furyl group, or thienyl group, l) a cyclic alkyl group with 3 to 6 carbon atoms, or m) a tetrahydrothiapyrane-4-yl group;
• with R1, R2, R3, and R4 being the same or different,
• proviso that neither R1 and R2 nor R3 and R4 are joined together to form a five-, six-, or seven-membered ring which may comprise nitrogen atoms, oxygen atoms, or sulfur atoms;
• wherein each of said one or more substituents on said phenyl group in c) and h) is halogen atom, alkyl group with 1 to 20 carbon atom, alkoxy group with 1 to 20 carbon atom, thiol group, nitro group, alkylamino group with 1 to 20 carbon atom, amino group, cyano group, hydroxyl group, alkylthio group with 1 to 20 carbon atom, carboxyl group, alkoxycarbonyl group with 1 to 20 carbon atom, acetamide group, or dimethylaminopropoxy group;
• R5 represents an unsubstituted alkyl group with 1 to 12 carbon atoms, a hydrogen atom, or a carboxyl group;
• R6 in (R6)n (wherein n is the number of substitutions of R6 and represents 1, 2, 3, 4, or 5) represents a hydrogen atom;
• and
• each of R7, R8, and R9 represents a hydrogen atom.