C-C chemokine receptor 3 proteins
AssigneeMillennium Pharmaceuticals, Inc.
InventorsCraig J. Gerard, Norma P. Gerard, Charles R. Mackay, Paul D. Ponath, Theodore W. Post, Shixin Qin
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Abstract
The present invention relates to isolated and/or recombinant C-C Chemokine Receptor 3 (CKR-3, CCR3) proteins or polypeptides.
Claims16
An isolated polypeptide comprising a mammalian C-C chemokine receptor 3 protein (CCR3), wherein said CCR3 has at least about 95% amino acid sequence identity with SEQ ID NO:2 or SEQ ID NO:6, and said CCR3 binds a ligand selected from the group consisting of RANTES and MCP-3.
An isolated polypeptide comprising a mammalian C-C chemokine receptor 3 protein (CCR3), wherein said CCR3 has at least about 95% amino acid sequence identity with SEQ ID NO:2 or SEQ ID NO:6, and said CCR3 binds eotaxin.
An isolated polypeptide comprising a C-C chemokine receptor 3 protein (CCR3), wherein the amino acid sequence of said CCR3 protein is selected from the group consisting of SEQ ID NO:2 and SEQ ID NO:6.
An isolated polypeptide comprising a mammalian C-C chemokine receptor 3 protein (CCR3) encoded by SEQ ID NO:1.
An isolated polypeptide comprising a mammalian C-C chemokine receptor 3 protein (CCR3) encoded by SEQ ID NO:5.
Dependencies are inferred from the claim text.