Methods and pharmaceutical compositions for healing wounds
AssigneeBar-Ilan University
InventorsTamar Tennenbaum, Sanford Sampson, Toshio Kuroki, Addy Alt, Shlomzlon Shen
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Abstract
A pharmaceutical composition and method for inducing or accelerating a healing process of a skin wound are described. The pharmaceutical composition contains, as an active ingredient, a therapeutically effective amount of an agent for either enhancing PKC production and/or enhancing PKC activation; and a pharmaceutically acceptable carrier. The method is effected by administering the composition to a wound.
Claims3
A method of inducing or accelerating a healing of a skin wound, comprising administering at cells of the skin wound a nucleic acid construct which comprises a polynucleotide encoding a protein kinase C selected from the group consisting of PKC-δ, PKC-η, and PKC-ζ, operably linked to a promoter capable of directing transcription of said polynucleotide in said cells, whereby said cells produce a recombinant said protein kinase C thereby inducing or accelerating the healing process of the skin wound.
Dependencies are inferred from the claim text.