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US 7,402,566 B2Granted
Peptide inhibitor of TGF-β growth factors
AssigneeThe Regents of the University of California
InventorsEthan Bier, Kweon Yu
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Abstract
A potent peptide inhibitor (SuperSog) of TGF-β family growth factor signaling, peptide variants thereof and nucleotide coding sequences therefore are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.
Claims2
A purified peptide consisting of the amino acid sequence of amino acids 1-292 of the Drosophila Sog protein.
Dependencies are inferred from the claim text.