Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof
AssigneeThomas Jefferson University
InventorScott A. Waldman
Life of this patent
Estimating the term…
Abstract
In vitro methods of determining whether or not an individual has metastasized colorectal cancer cells are disclosed. In vitro methods of determining whether or not tumor cells are colorectal in origin are disclosed. In vitro kits for practicing the methods of the invention and to reagents and compositions useful to practice the methods, for example as components in such in vitro kits of the invention are provided. Methods of and kits and compositions for analyzing tissue samples from the colon tissue to evaluate the extent of metastasis of colorectal tumor cells are disclosed.
Claims23
An in vitro method of determining whether or not an individual who has been diagnosed with colorectal cancer has metastatic colorectal cancer comprising the step of examining a lymph node sample from an individual to determine whether ST receptor protein or mRNA encoding ST receptor protein is present in said lymph node sample, wherein the presence of ST receptor protein or mRNA encoding ST receptor protein indicates that said individual has metastasized colorectal cancer.
An in vitro method of screening an individual for metastasic colorectal cancer comprising the step of analyzing a lymph node sample from an individual to determine the presence ST receptor protein or mRNA encoding ST receptor protein in said sample wherein the presence of ST receptor or mRNA encoding ST receptor protein is indicative of metastasized colorectal cancer.
Dependencies are inferred from the claim text.