Back to results
US 7,402,322 B2Granted
Methods of treatment for septic shock with urine extract
AssigneeBiotempt B.V.
InventorsNisar Ahmed Khan, Hubertus Franciscus Josef Savelkoul, Robbert Benner
Life of this patent
Estimating the term…
Abstract
The invention relates to the field of immunology. Specifically, the invention relates to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantation-related disease or inflammatory disease. The invention provides for an immunoregulator (IR), use of an IR in preparing a pharmaceutical composition for treating an immune-mediated disorder and a method for treating an immune-mediated disorder.
Claims3
A method for selecting an agent with a therapeutic effect against septic shock, said method comprising:
- providing at least a first and a second test animals of the same species prone to show signs of septic shock;
- administering to the first test animal a urine fraction obtained from a pregnant female mammal of the same or different species that elutes with an apparent molecular weight of 1 to 15 kilodaltons as determined by gel-permeation chromatography and administering to the second animal a control;
- inducing septic shock in the animals;
- and
- determining the development of septic shock in the animals,
- selecting a fraction as an agent with a therapeutic effect against septic shock if the first test animal shows a reduction of the development of septic shock in the first animal as compared to the second animal.
3 more elements
Dependencies are inferred from the claim text.