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US 7,397,026 B2Granted
Efficient electron transfer dissociation for mass spectrometry
AssigneeAgilent Technologies, Inc.
InventorJerry T Dowell
Life of this patent
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Abstract
The present invention relates to, inter alia, methods and apparatuses for electron transfer dissociation (ETD) that vary the internal energy of precursor ions for ETD. The methods and apparatuses are particularly useful in mass spectrometry.
Claims19
An apparatus for fragmenting analyte ions using electron transfer dissociation, comprising:
- (a) a heater and control system for establishing an internal temperature of the analyte ions;
- and
- (b) a reaction chamber for fragmenting the analyte ions of (a), wherein the fragmenting is performed by electron transfer dissociation.
A method for fragmenting analyte ions by electron transfer dissociation, comprising:
- (a) establishing an internal temperature of the analyte ions using a heater and control system;
- (b) contacting the analyte ions of (a) with anions in a reaction chamber for electron transfer dissociation.
Dependencies are inferred from the claim text.