Quinolinone-carboxamide compounds

A compound of formula (I):

• wherein:
• R1 is hydrogen, halo, hydroxy, C1-4alkyl, or C1-4alkoxy;
• R2 is C3-4alkyl or C3-6cycloalkyl;
• R3 is hydroxy, C1-3alkoxy, hydroxy-substituted C1-4alkyl, or —OC(O)NRaRb;
• R4 is hydrogen or C1-4alkyl;
• X is selected from —N(R8)C(O)R9, —N(R8)S(O)2R10, —S(R11)O2, —N(R8)C(O)OR12, —N(R8)C(O)NR13R14, —N(R8)SO2NR13R14, —C(O)NR13R14, —OC(O)NR13R14, —C(O)OR12, —OR15, and cyano;
• R5 is hydrogen or C1-4alkyl, wherein C1-4alkyl is optionally substituted with hydroxy, C1-3alkoxy, or cyano;
• R6 and R7 are independently selected from hydrogen, hydroxy, halo, and C1-4alkyl, wherein C1-4alkyl is optionally substituted with hydroxy or C1-3alkoxy;
• R8 is hydrogen or C1-4alkyl;
• or R5 and R8, R5 and R6, or R6 and R8 taken together form C2-5alkylenyl, wherein C2-5alkylenyl is optionally substituted with hydroxy, halo, hydroxy-substituted C1-3alkyl, or C1-3alkoxy;
• or R3 and R5 taken together form —OCH2CH2—;
• or R5 and R6 taken together form —(CH2)q—Q—(CH2)q, wherein Q is oxygen or sulfur and q is independently 0, 1, or 2;
• R9 is hydrogen, furanyl, or C1-4alkyl, wherein C1-4alkyl is optionally substituted with hydroxy or with from 1 to 3 halo;
• R10 is hydrogen or C1-4alkyl, wherein C1-4alkyl is optionally substituted with —SO2Rc, C3-6cycloalkyl or with from 1 to 3 halo;
• or R8 and R10 taken together form C3alkylenyl;
• R11 is hydrogen, C1-4alkyl, or —NRbRc;
• or R5 and R11 or R6 and R11 taken together form C2-5alkylenyl;
• R12, R13, and R14 are independently hydrogen or C1-4alkyl;
• R15 is hydrogen or C1-4alkyl, wherein C1-4alkyl is optionally substituted with hydroxy;
• Ra, Rb, and Rc are independently hydrogen or C1-3alkyl;
• and
• n is 1, 2, 3, or 4;
• provided that when n is 1, X forms a carbon-carbon bond with the carbon atom bearing the substituents R6 and R7;
• or a pharmaceutically-acceptable salt or stereoisomer thereof.