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US 7,396,832 B2Granted
Inhibitors of Akt activity
AssigneeMerck & Co., Inc.
InventorsCraig W. Lindsley, Zhijian Zhao
Life of this patent
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Abstract
The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention
Claims8
A compound which is:
- N-[4-(3-phenylquinoxalin-2-yl)benzyl]propane-1-sulfonamide or the TFA salt thereof.
A compound which is selected from:
- R
- or a pharmaceutically acceptable salt or a stereoisomer thereof.
Dependencies are inferred from the claim text.