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AssigneeNational Institute of Advanced Industrial Science and Technology
InventorsHisashi Narimatsu, Takashi Kudo, Akira Togayachi, Toru Hiruma
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A tumor marker nucleic acid of the present invention is concerned with a nucleic acid hybridizing under stringent conditions to a nucleotide sequence described in SEQ ID NO: 1 or a complementary nucleotide sequence thereof. A method of testing canceration of the present invention is a method comprising diagnosing a biological sample as being cancerous when the transcription level of the nucleic acid in the biological sample significantly exceeds that in a normal biological sample as a control. The present invention also relates to a β1,3-N-acetyl-D-glucosaminyltransferase protein having an activity of transferring N-acetyl-D-glucosamine from a donor substrate to an acceptor substrate through β1,3-linkage.
An isolated β1,3-N-acetyl-D-glucosaminyltransferase protein comprising the amino acid sequence of SEQ ID NO:
A method for transferring N-acetyl-D-glucosamine from a donor substrate to an acceptor substrate through β1,3-linkage, the method comprising reacting the donor substrate and the acceptor substrate in the presence of a β1,3-N-acetyl-D-glucosaminyltransferase protein, wherein the protein comprises the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.