Preparation for cardio-cerebral blood vessel diseases and its preparing method
AssigneeTianjin Tasly Pharmaceutical Co., Ltd.
InventorsYiyu Cheng, Haijiang Zhang, Zhengliang Ye
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AssigneeTianjin Tasly Pharmaceutical Co., Ltd.
InventorsYiyu Cheng, Haijiang Zhang, Zhengliang Ye
Estimating the term…
The present invention discloses a traditional Chinese medicine preparation for cardio-cerebral blood vessel diseases, it is prepared through extracting danshen and Notoginseng by lye, precipitating with alcohol, concentrating, and adding other medicine and excipients. Then using the HAPLY-MS and HAPLY fingerprint Atlas to characterize its Physicochemical properties completely. Using the fingerprint Atlas analysis method of the present invention, the structure and comparative content of biologically active component can be known. Characterization of the physical chemical properties of danshen and Notoginseng of traditional Chinese medicine preparation with this way is better than other methods of the prior art.
A preparation for the treatment of cardiovascular and cerebrovascular diseases, characterized in that it comprises two components both having a quasi-molecular ion mass peak m/z of 537[M-H]−, a second fragment ion m/z of 493[M-H-CO2]− and 295[M-CO2-R-H2O]−, and a third fragment ion m/z of 159 and 109, with the maximum absorption wave length of 327 nm, wherein the mass spectrum analysis is carried out as follows:
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