Electroprocessed material made by simultaneously electroprocessing a natural protein polymer and two synthetic polymers
AssigneeVirginia Commonwealth University Intellectual Property Foundation
InventorsGary L. Bowlin, Gary E. Wnek, David G. Simpson
Life of this patent
Estimating the term…
Abstract
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more natural materials, one or more synthetic materials, or a combination thereof. The substance can be one or more therapeutic or cosmetic substances or other compounds, molecules, cells, vesicles. The compositions can be used in substance delivery, including drug delivery within an organism by, for example, releasing substances or containing cells that release substances. The compositions can be used for other purposes, such as prostheses or similar implants.
Claims19
A composition comprising:
- an electroprocessed material and a substance, wherein the electroprocessed material is made by a method comprising the step of simultaneously electroprocessing a natural polymer that is an extracellular matrix protein or polymerized thrombin and two or more synthetic polymers, wherein the synthetic polymers are selected from the group consisting of poly(urethanes), poly(siloxanes), silicones, poly(ethylene), poly(vinyl pyrrolidone), poly(2-hydroxyethyl methacrylate), poly(N-vinyl pyrrolidone), poly(methyl methacrylate), poly(vinyl alcohol), poly(acrylic acid), polyacrylamide, poly(ethylene-co-vinyl acetate), poly(ethylene glycol), poly(methacrylic acid), polyactides (PLA), polyglycolides (PGA), poly(lactide-co-glycolides) (PLGA), polyanhydrides and polyorthoesters, and, wherein the substance comprises a therapeutic substance, a cosmetic substance or a combination thereof.
A composition comprising an electroprocessed material, wherein the electroprocessed material is made by a process comprising the step of simultaneously electroprocessing a solution comprising a natural polymer that is an extracellular matrix protein or polymerized thrombin and two or more synthetic polymers, wherein the synthetic polymers are selected from the group consisting of poly(urethanes), poly(siloxanes), silicones, poly(ethylene), poly(vinyl pyrrolidone), poly(2-hydroxy ethyl methacrylate), poly(N-vinyl pyrrolidone), poly(methyl methacrylate), poly(vinyl alcohol), poly(acrylic acid), polyacrylamide, poly(ethylene-co-vinyl acetate), poly(ethylene glycol), poly(methacrylic acid), polylactides (PLA), polyplycolides (PGA), poly(lactide-co-glycolides) (PLGA), polyanhydrides and polyorthoesters.
A composition comprising:
- an electroprocessed material, wherein the electroprocessed material is made by a process comprising the step of simultaneously electroprocessing from a solution a natural polymer that is an extracellular matrix protein or polymerized thrombin and two or more synthetic polymers, wherein the synthetic polymers are selected from the group consisting of poly(urethanes), poly(siloxanes), silicones, poly(ethylene), poly(vinyl pyrrolidone), poly(2-hydroxy ethyl methacrylate), poly(N-vinyl pyrrolidone), poly(methyl methacrylate), poly(vinyl alcohol), poly(acrylic acid), polyacrylamide, poly(ethylene-co-vinyl acetate), poly(ethylene glycol), poly(methacrylic acid), polylactides (PLA), polyglycolides (PGA), poly(lactide-co-glycolides) (PLGA), polyanhydrides and polyorthoesters, and wherein the electroprocessing is selected from the group consisting of electrospraying, electrosputtering, electrospinning or electroaerosol treatment of the solution.
Dependencies are inferred from the claim text.