Apparatus and method for separating and concentrating fluids containing multiple components
AssigneeBiomet Biologics, LLC
InventorsMichael Leach, Jennifer E. Woodell-May, Joel C. Higgins, Brandon Miller
Life of this patent
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Abstract
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
Claims20
A system for separating a multi-component fluid from a patient with centrifugation, the system comprising:
- a container, having a bottom and a side wall extending from said bottom, defining a sample holding area;
- a buoy disposed in said sample holding area;
- a member to selectively close a top of said container;
- and
- a conduit interconnecting the patient and a port defined by said container;
- wherein said buoy is movable when acted upon by forces created during the centrifugation;
- wherein said buoy defines a collection volume for collecting a selected component of the multi-component fluid.
A system for separating a multi-component fluid from a patient with centrifugation, the system comprising:
- a container, having a bottom and a side wall extending from said bottom defining a sample holding area;
- a buoy disposed in said sample holding area;
- a member to selectively close a top of said container;
- and
- wherein said buoy is movable when acted upon by forces created during the centrifugation;
- wherein said buoy defines a collection surface for collecting a selected component of the multi-component fluid;
- wherein said collection surface generally defines a cone extending from a plane defined by said piston and having an apex within said piston.
A system for separating a multi-component fluid from a patient with centrifugation, the system comprising:
- a container, having a bottom and a side wall extending from said bottom, defining a sample holding area;
- a buoy having a first density disposed in said sample holding area;
- a member to selectively close a top of said container;
- and
- a piston having a second density;
- a connection member operably interconnecting said buoy and said piston;
- wherein said buoy is movable when acted upon by forces created during the centrifugation;
- wherein said buoy defines a collection surface for collecting a selected component of the multi-component fluid;
- wherein a selected fraction is operable to be collected near said collection surface between said buoy and said piston.
A system for separating a multi-component fluid from a patient with centrifugation, the system comprising:
- a container, having a bottom and a side wall extending from said bottom defining a sample holding area;
- a buoy disposed in said sample holding area;
- a member to selectively close a top of said container;
- and
- wherein said buoy is movable when acted upon by forces created during the centrifugation;
- wherein said buoy defines a collection volume for collecting a selected component of the multi-component fluid;
- wherein said buoy includes a selected density such that said buoy is able to achieve a selected position between two components of a multi-component fluid during the centrifugation.
A system for separating a multi-component fluid from a patient with centrifugation, the system comprising:
- a container, having a bottom and a side wall defining a selectable cross-section dimension extending from said bottom, defining a sample holding area, wherein the selectable cross-section dimension is selectable between a first small dimension and a second large dimension;
- a buoy disposed in said sample holding area operable to contact the sidewall in the first small dimension and not contact at least a portion of the sidewall when in the second large dimension;
- a member to selectively close a top of said container;
- and
- a conduit interconnecting the patient and a port defined by said container
- wherein said buoy is movable when acted upon by forces created during the centrifugation;
- wherein said buoy defines a collection surface for collecting a selected component of the multi-component fluid.
Dependencies are inferred from the claim text.