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US 7,374,544 B2Granted
Method and apparatus for penetrating tissue
AssigneePelikan Technologies, Inc.
InventorsDominique M. Freeman, Dirk Boecker, Don Alden
Life of this patent
Estimating the term…
Abstract
These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 mL of the fluid.
Claims59
A body fluid sampling system for use on a tissue site, the system comprising:
- a controllable, electrically powered drive force generator;
- a penetrating member operatively coupled to said controllable, electrically powered drive force generator, said controllable, electrically powered force generator moving said penetrating member along a path out of a housing having a penetrating member exit, into said tissue site, stopping in said tissue site, and withdrawing out of said tissue site;
- and
- a sample chamber that includes electrodes, has a volume no greater than 1 μL and has an analyte sensor, the sample chamber being positioned to receive fluid from a wound created by said penetrating member, and the analyte sensor and determine a concentration of an analyte in a fluid using a sample of less than 1 μL of the fluid, wherein when the penetrating member is removed from the sample chamber, the electrodes remain in the sample chamber and the volume of the sample chamber is less than 1 μL and
- a penetrating member sensor coupled to said controllable, electrically powered drive force generator and to a programmable processor, the penetrating member sensor configured to provide information relative to a depth of penetration of a penetrating member through a skin surface, the programmable processor operatively programmed with software that has control instructions for the controllable, electrically powered drive force generator to keep a wound tract created by a penetrating member open for a sufficient time to provide for spontaneous flow of blood for sample capture into an associated sample chamber, wherein the control instructions are selected from at least one of, penetration depth of a penetrating member, velocity of a penetrating member, velocity of a penetrating member in or out of target tissue and a dwell time of a penetrating member in the tissue site.
2 more elements
A body fluid sampling system for use on a tissue site, the system comprising:
- a controllable, electrically powered drive force generator;
- a plurality of cartridges each containing a penetrating member, each of said cartridges coupled together to define a flexible array;
- a transport device for moving each of said cartridges into a launch position operatively coupling said penetrating member to the force generator;
- an analyte detecting member positioned to receive fluid from a wound created by said penetrating member, said detection member configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid;
- and
- a programmable processor operatively programmed with software that has control instructions for the controllable, electrically powered drive force generator to keep a wound tract created by a penetrating member open for a sufficient time to provide for spontaneous flow of blood for sample capture into an associated sample chamber, wherein the control instructions are selected from at least one of, penetration depth of a penetrating member, velocity of a penetrating member, velocity of a penetrating member in or out of target tissue and a dwell time of a penetrating member in the tissue site.
3 more elements
A body fluid sampling system for use on a tissue site, the system comprising:
- a controllable, electrically powered drive force generator;
- a penetrating member having an elongate portion without a molded attachment and operatively coupled to said force generator;
- a sterility enclosure covering at least a tip of said penetrating member, said sterility enclosure removed from said penetrating member prior to actuation of the member and positioned so that the penetrating member will not contact said enclosure during actuation;
- an analyte detecting member positioned to receive fluid from a wound created by said penetrating member, said detection member configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid;
- and
- a programmable processor operatively programmed with software that has control instructions for the controllable, electrically powered drive force generator to keep a wound tract created by a penetrating member open for a sufficient time to provide for spontaneous flow of blood for sample capture into an associated sample chamber, wherein the control instructions are selected from at least one of, penetration depth of a penetrating member, velocity of a penetrating member, velocity of a penetrating member in or out of target tissue and a dwell time of a penetrating member in the tissue site.
3 more elements
A body fluid sampling system for use on a tissue site, the system comprising:
- a controllable, electrically powered drive force generator;
- a penetrating member having an elongate portion without a molded attachment and operatively coupled to said force generator;
- a sterility enclosure creating a sterile environment around at least a tip of said penetrating member, said penetrating member breaching said sterile environment during actuation;
- an analyte detecting member positioned to receive fluid from a wound created by said penetrating member, said detection member configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid;
- and
- a programmable processor operatively programmed with software that has control instructions for the controllable, electrically powered drive force generator to keep a wound tract created by a penetrating member open for a sufficient time to provide for spontaneous flow of blood for sample capture into an associated sample chamber, wherein the control instructions are selected from at least one of, penetration depth of a penetrating member, velocity of a penetrating member, velocity of a penetrating member in or out of target tissue and a dwell time of a penetrating member in the tissue site.
3 more elements
Dependencies are inferred from the claim text.