Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
AssigneesExact Sciences Corporation, Mayo Foundation for Medical Education and Research
InventorsAnthony P. Shuber, David A. Ahlquist
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Abstract
The invention provides methods and materials for detecting supracolonic aerodigestive premalignant and malignant neoplasms. Specifically, the invention provides methods and materials for determining whether a stool sample from a mammal contains a neoplasm-specific marker from a neoplsm located in the supracolonic aerodigestive tissue of a mammal.
Claims28
A method for detecting a lung neoplasm in a mammal, said method comprising:
- detecting a nucleic acid marker indicative of a neoplasm in a stool sample obtained from a mammal;
- and,
- performing an additional cancer screening technique and detecting a neoplasm present in the lung of the mammal.
A method of screening a mammal for the presence of a lung neoplasm, the method comprising:
- detecting a nucleic acid marker indicative of a neoplasm in a stool sample obtained from a mammal;
- and,
- performing an additional cancer screening to determine whether a neoplasm is present in the lung of the mammal.
A method of screening a mammal for the presence of a lung neoplasm, the method comprising:
- performing a cancer screening to determine whether a neoplasm is present in the lung of a mammal based on the knowledge that a nucleic acid marker indicative of a neoplasm present in a stool sample.
Dependencies are inferred from the claim text.