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US 7,364,657 B2Granted
Integrated system for on-site cell acquisition, processing, and delivery
AssigneeAbbott Cardiovascular Systems Inc.
InventorsEvgenia Mandrusov, Albert K. Chin, William Earl Webler, Jr., Yan Shen, Robert D. Ainsworth, Eugene Michel
Life of this patent
Estimating the term…
Abstract
Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate mononuclear cells, which can then be delivered back near the cardiac tissue of the patient.
Claims22
A system, comprising;
- a cell processing device to separate mononuclear cells from a bone marrow extract, the cell processing device comprising a first syringe coupled to a second syringe and a rotating mechanism coupled to the first syringe;
- and
- a first container;
- a gradient solution for the cell processing device in the first container;
- a second container;
- and
- a washing solution for the cell processing device in the second container,
- the first container and the second container coupled to the cell processing device with a network of tubes.
5 more elements
A cell processing system, comprising:
- a mixture comprising a density gradient solution, a washing solution, and a bone marrow extract;
- a first syringe coupled to a secondary syringe of a processing set;
- a filter coupled to the first syringe and the second syringe;
- a washing solution;
- means for drawing the mixture into the first syringe configured to separate mononuclear cells from a bone marrow extract;
- means for spinning the first syringe to separate the mixture into a layer of mononuclear cells and a layer of waste fluid;
- means for passing the layer of mononuclear cells through the filter coupled to the first syringe and the second syringe to collect the mononuclear cells in the filter;
- means for drawing the washing solution through the filter and into the second syringe to wash out the mononuclear cells for collection of the mononuclear cells in the second syringe.
5 more elements
Dependencies are inferred from the claim text.