4′,4″-substituted 3α-(diphenylmethoxy) tropane analogs for treatment of mental disorders
AssigneeP2D, Inc.
InventorFrank P. Zemlan
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Abstract
The present invention describes a method for the treatment of attention deficit hyperactivity disorder (ADHD), conduct disorder, alcohol addiction, tobacco addiction, nicotine addiction, parkinsonism including Parkinson's disease, female and male orgasmic disorders, female and male sexual arousal disorders, hypoactive sexual desire disorder, and disorders characterized by anxiety and/or depression. In this method, a therapeutically effective, nontoxic dose of a 4′,4″-substituted 3α-(diphenylmethoxy) tropane analog or a pharmaceutically acceptable salt thereof is administered to the patient in need of such treatment.
Claims12
A method for treating attention deficit hyperactivity disorder, comprising administering to a patient in need of such treatment a safe and effective amount of a compound having the formula:
- in which R is selected from hydrogen, alkyl, alkoxy, arylalkyl, aryloxyalkyl, cinnamyl, and acyl;
- and
- R1 and R2 are independently selected from hydrogen, alkyl, alkoxy, hydroxy, halogen, cyano, amino and nitro;
- with the proviso that if R is methyl, R1 and R2 are not both hydrogen.
Dependencies are inferred from the claim text.