Pancreatic cancer secreted targets and uses thereof
AssigneeApplera Corporation
InventorsIan McCaffey, Kim Alving, Bruno Domon, Steven Ruben
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Abstract
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAST) and antibodies binds to PCAST. The present invention provides that PCAST is used as targets for screening agents that modulates the PCAST activities. Further the present invention provides methods for treating diseases associated with pancreas.
Claims15
A method of assessing pancreatic cancer in an individual, the method comprising detecting a KLK11 protein, set forth as an amino acid sequence comprising SEQ ID NO:10, in a sample from the individual, wherein the presence of the KLK11 protein is indicative of pancreatic cancer.
Dependencies are inferred from the claim text.