Method of fluorination
AssigneeMitsubishi Gas Chemical Company, Inc.
InventorsShoji Hara, Tsuyoshi Fukuhara
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AssigneeMitsubishi Gas Chemical Company, Inc.
InventorsShoji Hara, Tsuyoshi Fukuhara
Estimating the term…
A method of fluorination comprising reacting monosaccharides, oligosaccharides, polysaccharides, composite saccharides formed by bonding of these saccharides with proteins and lipids and saccharides having polyalcohols, aldehydes, ketones and acids of the polyalcohols, and derivatives and condensates of these compounds with a fluorinating agent represented by general formula (I) thermally or under irradiation with microwave or an electromagnetic wave having a wavelength around the microwave region. In accordance with the method, the fluorination at a selected position can be conducted safely at a temperature in the range of 150 to 200° C. where the reaction is difficult in accordance with conventional methods. The above method comprising the irradiation with microwave or an electromagnetic wave having a wavelength around the microwave region can be applied to substrates other than saccharides
A method of fluorination which comprises fluorinating a monosaccharide or monosaccharide bonded to a base of a nucleic acid using a fluorinating agent represented by general formula (I):
A method of fluorination which comprises fluorinating a monosaccharide or monosaccharide bonded to a base of a nucleic acid by bringing the monosaccharide or monosaccharide bonded to a base of a nucleic acid and a fluorinating agent represented by the general formula (II):
Dependencies are inferred from the claim text.