Sulfonamide derivatives for the treatment of diseases

A compound of the formula (1):

• or a pharmaceutically acceptable salt, isomer, or tautomer thereof, wherein:
• the (CH2)n—C(═O)Q1 group is in the meta or para position;
• R1 and R2 are independently selected from H and C1-C4 alkyl;
• n is 0, 1 or 2;
• and
• Q1 is selected from:
• and *—NR11-Q2-A;
• p is 1 or 2;
• Q2 is C1-C4 alkylenyl;
• R11 is H or C1-C4 alkyl;
• A is pyridyl;
• C3-C10 cycloalkyl, said cycloalkyl being optionally bridged by one or more carbon atoms;
• tetrahydropyranyl;
• piperidinyl optionally substituted with benzyl;
• tetrahydrothiopyranyl;
• or
• R3, R4, R5, R6 and R7 are independently H, C1-C4 alkyl, OR8, SR9, halo, CN, CF3, OCF3, COOR9, SO2NR9R10, CONR9R10, NR9R10, NHCOR10 or phenyl;
• R8 is C1-C4 alkyl;
• R9 and R10 are independently H or C1-C4 alkyl;
• and
• the * represents the attachment point to the carbonyl group of formula (1).