Method for neuronal protection in amyotrophic lateral sclerosis by a vaccine comprising Copolymer-1 or Copolymer-1 related peptides
AssigneeYeda Research and Development Co. Ltd.
InventorsMichal Eisenbach-Schwartz, Esther Yoles, Jonathan Kipnis
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Abstract
A vaccine for reducing disease progression, and/or protection of motor nerve degeneration, and/or protection from glutamate toxicity in motor neurone disease (MND), particularly amyotrophic lateral sclerosis (ALS), patients, comprising an active agent selected from the group consisting of Cop 1, a Cop 1-related peptide, a Cop 1-related polypeptide, and poly-Glu, Tyr. The active agent is preferably Cop 1 or poly-Glu, Tyr, and can be administered with or without an adjuvant.
Claims11
A method for protection against motor nerve degeneration, and/or protection from glutamate toxicity in a patient suffering from amyotrophic lateral sclerosis (ALS), which comprises immunizing said patient with a vaccine comprising a therapeutically effective amount of an active agent selected from the group consisting of Copolymer 1, a Copolymer 1-related peptide, and a Copolymer 1-related polypeptide.
Dependencies are inferred from the claim text.