Retroviral vector
AssigneeOxford Biomedica (UK) Limited
InventorsKyriacos Mitrophanous, Mary Collins, Yasuhiro Takeuchi, Yasuhiro Ikeda
Life of this patent
Estimating the term…
Abstract
Provided herein is a retroviral vector comprising, and capable of expressing, a nucleotide of interest (NOI), wherein the NOI encodes an RNA or protein which is harmful to a cell.
Claims14
A method for producing a stable lentiviral packaging cell comprising transducing a cell with a retroviral vector comprising a nucleotide sequence encoding lentiviral Gag-Pol, wherein the retroviral vector is of different viral origin than a lentivirus, and wherein the lentiviral packaging cell stably produces lentiviral Gag-Pol continuously for at least 3 months.
A stable lentiviral packaging cell, wherein the packaging cell comprises a retroviral vector comprising a nucleotide sequence encoding lentiviral Gag-Pol, wherein the retroviral vector is of different viral origin than a lentivirus, and wherein the lentiviral packaging cell stably produces lentiviral Gag-Pol continuously for at least 3 months.
Dependencies are inferred from the claim text.