Polyester/cyanoacrylate tissue adhesive compositions
AssigneePoly-Med, Inc.
InventorsShalaby W. Shalaby, M. Aaron Vaughn
Life of this patent
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Abstract
This invention addresses absorbable cyanoacrylate-based tissue adhesive compositions based primarily on an alkoxy cyanoacrylate combined with one or more alkyl cyanoacrylate(s), a stabilizer against premature anionic polymerization, and/or an absorbable polymeric modifier with improved, and preferably, functional properties for use, primarily, for internal wound repair applications.
Claims14
A cyanoacrylate-based absorbable tissue adhesive composition, comprising a blend of at least one alkoxyalkyl cyanoacrylate and at least one alkyl cyanoacrylate, the ratio of alkoxyalkyl cyanoacrylate to alkyl cyanoacrylate comprising from about 60:40 to about 99:1 by weight, and further comprising greater than 2 percent by weight of a polymeric modifier comprising a copolymer of trimethylene carbonate and at least one additional cyclic monomer selected from the group consisting of glycolide, lactide, p-dioxanone, 1,5-dioxepan-2-one, and ε-caurolactone.
Dependencies are inferred from the claim text.