Drug-eluting stent having collagen drug carrier chemically treated with genipin
OwnerHsing-Wen Sung, Mei-Chin Chen +2inventors
InventorsHsing-Wen Sung, Mei-Chin Chen, Peter Y Tu, Hosheng Tu
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Abstract
A method for treating vulnerable plaques of a patient, comprising: providing a biodegradable stent comprising a first supporting zone made of a first biodegradable material, wherein the supporting zone comprises at least a portion of continuous circumference of the stent; and a second therapeutic zone made of a second biodegradable material, wherein the therapeutic zone comprises at least one bioactive agent; delivering the biodegradable stent to the vulnerable plaques; orienting the therapeutic zone at about the luminal surface of the vulnerable plaque; and releasing the at least one bioactive agent for treating the vulnerable plaques.
Claims12
A biodegradable stent for treating vulnerable plaques or atherosclerotic plaques of a patient comprising:
- at least two zones, wherein a first supporting zone comprises a first biodegradable material;
- a second therapeutic zone comprising a second biodegradable material, wherein at least one of the first and the second biodegradable material comprises at least one bioactive agent and wherein the at least one bioactive agent comprises lipostabil.
A biodegradable stent for treating vulnerable plaques or atherosclerotic plaques of a patient comprising:
- at least two zones, wherein a first supporting zone comprises a first biodegradable material;
- a second therapeutic zone comprising a second biodegradable material, wherein at least one of the first and the second biodegradable material further comprises a biological material, wherein said biological material is crosslinked with a crosslinking agent or with ultraviolet irradiation;
- and
- wherein the crosslinking agent is genipin, its analog, derivatives, and combination thereof.
Dependencies are inferred from the claim text.