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US 7,351,389 B2Granted
Aminocarboxylate ligands having substituted aromatic amide moieties
AssigneeBracco International B.V.
InventorsRadhakrishna K. Pillai, Sang I. Kang, Edmund R. Marinelli, Ramachandran S. Ranganathan, Michael F. Tweedle
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Abstract
Novel metal-chelate complexes comprising aminocarboxylate ligands including substituted aromatic amide moieties, such as those having the formula wherein R13, A1, R1 and R2 are as defined herein, are disclosed.
Claims5
A compound of the formula
- wherein
- A1 is —(CH2)m′ or a single bond;
- (CH2)m and (CH2)m′ may independently be substituted with alkyl or hydroxyalkyl;
- R1 and R2 are each independently hydrogen or
- with the proviso that at least one of R1 and R2 must be other than hydrogen;
- R3 and R4 are independently hydrogen, alkyl, arylalkyl, aryl, alkoxy and hydroxyalkyl;
- R12 is hydrogen, alkyl or hydroxyalkyl;
- R13 is hydrogen, alkyl, arylalkyl, aryl, alkoxy or hydroxyalkyl;
- m and m′ are independently 1 to 5;
- and multimeric forms thereof.
7 more elements
Dependencies are inferred from the claim text.