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US 7,351,380 B2Granted
Microfluidic structures and methods for integrating a functional component into a microfluidic device
AssigneeSandia Corporation
InventorsBlake Simmons, Linda Domeier, Noble Woo, Timothy Shepodd, Ronald F. Renzi
Life of this patent
Estimating the term…
Abstract
Injection molding is used to form microfluidic devices with integrated functional components. One or more functional components are placed in a mold cavity which is then closed. Molten thermoplastic resin is injected into the mold and then cooled, thereby forming a solid substrate including the functional component(s). The solid substrate including the functional component(s) is then bonded to a second substrate which may include microchannels or other features.
Claims8
A microfluidic device comprising:
- a first substrate comprising a resin and having upper and lower surfaces;
- a plurality of flow connectors embedded in the first substrate, the plurality of flow connectors comprising
- first and second ends, the second end projecting from the upper surface of the substrate and the first end being substantially flush with the lower surface of the substrate;
- a flow path extending between the first and second ends;
- a flange extending radially outward proximate the first end;
- a coupling face positioned between the first end and the flange;
- and
- an annular groove circumscribing the coupling face;
- a second substrate bonded to the first substrate, the second substrate comprising
- an upper and a lower surface, the upper surface being bonded to the lower surface of the first substrate;
- one or more fluid channel embedded therein;
- and
- a plurality of inlets in fluid communication with at least one of the one or more fluid channels, the inlets located in correspondence with the flow connectors and extending through the upper surface of the second substrate.
10 more elements
A microfluidic device comprising:
- a first substrate comprising a resin and having upper and lower surfaces;
- a plurality of flow connectors embedded in the first substrate, the plurality of flow connectors comprising
- first and second ends, the second end projecting from the upper surface of the substrate and the first end being substantially flush with the lower surface of the substrate;
- a flow path extending between the first and second ends;
- a flange extending radially outward proximate the first end;
- a coupling face positioned between the first end and the flange;
- and
- a second substrate bonded to the first substrate, the second substrate comprising
- an upper and a lower surface, the upper surface being bonded to the lower surface of the first substrate;
- one or more fluid channel embedded therein;
- and
- a plurality of inlets in fluid communication with at least one of the one or more fluid channels, the inlets located in correspondence with the flow connectors and extending through the upper surface of the second substrate.
9 more elements
Dependencies are inferred from the claim text.