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US 7,348,427 B2Granted
Antipathogenic benzamide compounds
AssigneeGeneSoft Pharmaceuticals, Inc.
InventorsRoland W. Bürli, Jacob Kaizerman, Peter Jones
Life of this patent
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Abstract
Antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.
Claims5
A compound having the formula
- wherein i is 3;
- one of X1, X2, and X3 is a ring vertex selected from the group consisting of —O—, —S—, and —NR2—, and the other two of X1, X2, and X3 are ring vertices selected from the group consisting of ═N— and ═CR4—, wherein each moiety
- is the same or different and at least one moiety is other than
- each R1 is independently H, F, Cl, CN, CF3, OH, N(R2)2, OR2 or a substituted or unsubstituted (C1-C12)alkyl group, with the proviso that at least one R1 is F, Cl, CN or CF3;
- each R2 and R3 is independently H or a substituted or unsubstituted (C1-C12)alkyl group;
- each R4 is independently H, F, Cl, Br, I, CN, OH, NO2, NH2, or a substituted or unsubstituted (C1-C12)alkyl group;
- Z(R2)n is a member selected from the group consisting of:
- r is an integer ranging from 2 to 8, inclusive;
- each R25 is independently selected from the group consisting of H, CH3, CH2CH3, CH2CH2CH3, or CH(CH3)2;
- said compound having at least one basic group having a pKb of 12 or less or a quaternized nitrogen group.
7 more elements
Dependencies are inferred from the claim text.