Extraction of pharmaceutically active components from plant materials
AssigneeGW Pharma Limited
InventorsBrian Whittle, Colin A. Hill, Ian R. Flockhart, David Victor Downs, Peter Gibson, Gary William Wheatley
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Abstract
The invention relates to the extraction of pharmaceutically active components from plant materials, and more particularly to the preparation of a botanical drug substance (BDS) for incorporation in to a medicament. It also relates to a BDS of given purity, for use in pharmaceutical formulations. In particular it relates to BDS comprising cannabinoids obtained by extraction from cannabis.
Claims21
A method of extracting cannabinoids from plant material comprising a decarboxylation step, an extraction with liquid carbon dioxide (CO2), and a step to reduce the proportion of non-target materials in the extract, characterised in that the extraction with liquid CO2 is conducted under sub-critical conditions at a temperature in the range of from 5 to 15° C. and a pressure in the range of from 50 to 70 bar.
Dependencies are inferred from the claim text.