Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
AssigneeIsis Pharmaceuticals, Inc.
InventorsStanley T. Crooke, David J. Ecker, Rangarajan Sampath, Susan M. Freier, Christian Massire, Steven A. Hofstadler, Kristin Sannes Lowery, Eric E. Swayze, Brenda F. Baker, C. Frank Bennett
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Abstract
The present invention provides design and synthesis of oligomeric compounds and compositions that can be administered to reduce the activity of SARS virus in vivo or in vitro, to prevent or treat SARS virus-associated disease, to detect AARS virus, and to diagnose SARS virus-associated diseases.
Claims18
An antisense oligonucleotide 12 to 50 nucleobases in length targeted to nucleobases 2 to 73 of a nucleic acid molecule encoding severe acute respiratory syndrome (SARS) virus (SEQ ID NO:
- 29752), wherein said oligonucleotide specifically hybridizes with the nucleic acid molecule encoding SARS virus.
Dependencies are inferred from the claim text.