Arrays of microparticles and methods of preparation thereof
AssigneeBio Array Solutions Ltd.
InventorsMichael Seul, Chiu Wo Chau, Hui Huang, Sukanta Banerjee, Jiacheng Yang, Ye Hong
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Abstract
This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.
Claims12
A method for producing biochips comprising patterning a substrate, having at least one surface, to form a plurality of biochip regions;
- by inscribing the substrate between the chip regions;
- assembling bead arrays comprising many differently optically encoded beads having biomolecules attached thereto said biomolecues being identified by said optical encoding, said assembly occurring on a surface of the substrate within several of the biochip regions but without encoding the location of each biochip region within the substrate;
- and singulating the substrate along at least some of the inscriptions to form a plurality of individual biochips with assembled bead arrays thereon.
Dependencies are inferred from the claim text.