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AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsSatoshi Nakagawa, Hiroshi Mizoguchi, Seiko Ando, Mikiro Hayashi, Keiko Ochiai, Haruhiko Yokoi, Naoko Tateishi, Akihiro Senoh, Masato Ikeda, Akio Ozaki
Estimating the term…
Novel polynucleotides derived from microorganisms belonging to coryneform bacteria and fragments thereof, polypeptides encoded by the polynucleotides and fragments thereof, polynucleotide arrays comprising the polynucleotides and fragments thereof, recording media in which the nucleotide sequences of the polynucleotide and fragments thereof have been recorded which are readable in a computer, and use of them.
An isolated DNA encoding a polypeptide having homoserine dehydrogenase activity, comprising an amino acid sequence of homoserine dehydrogenase derived from a microorganism belonging to the genus Corynebacterium in which the Val residue at the position corresponding to the 59th position in the amino acid sequence of SEQ ID NO:6952 is replaced with an amino acid residue other than a Val residue, or a polypeptide comprising an amino acid sequence in which the Val residue at the 59th position in the amino acid sequence of SEQ ID NO:6952 is replaced with an amino acid residue other than a Val residue, wherein the Val residue at the 59th position is optionally replaced with an Ala residue.
Dependencies are inferred from the claim text.