High-efficiency fusogenic vesicles, methods of producing them, and pharmaceutical compositions containing them
AssigneePevion Biotech Ltd.
InventorsSonia Vadrucci, Joseph Brunner, Rinaldo Zurbriggen
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel fusogenic vesicles as highly efficient and versatile encapsulation systems for delivering a substance of choice, such as nucleic acids, proteins, peptides, antigens, pharmaceutical drugs and cosmetic agents to cells and tissues.
Claims13
A fusogenic vesicle encapsulating at least one therapeutic or immunologically active substance, said fusogenic vesicle comprising a first viral fusion protein, wherein the first viral fusion protein is X-31 hemagglutinin (HA) and at least one other viral fusion protein selected from the group consisting of influenza virus, VSV, SFV, Sendai virus, and HIV, wherein the at least one other viral fusion protein causes fusion at a different temperature than X-31 HA.
Dependencies are inferred from the claim text.