Generator for rhenium-188
AssigneeLynntech, Inc.
InventorsAlan Cisar, Todd Adams, Paul Sylvester
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Abstract
Radioisotope generators comprising inorganic layered hydroxide composition, such as magnesium aluminates and lithium aluminates. These inorganic layered hydroxides form anion exchange materials that exhibit surprisingly high selective affinities for certain radioisotopes. Inorganic layered hydroxides have been prepared and shown to have high affinity for tungstate anions, the anion form of tungsten-188, yet low affinity for perrhenate anions, the anion form of rhenium-188.
Claims53
A rhenium-188 generator comprising an elutable container defining an eluant flow path, the container containing a matrix comprising a substantially non-elutable inorganic layered hydroxide compound containing tungsten-188.
A radionuclide generator for producing rhenium-188 comprising an insoluble inorganic layered hydroxide matrix including a tungstate compound containing tungsten-188, the matrix being permeable to fluid passage and permitting diffusion of rhenium-188 therethrough.
A process for preparing a radionuclide generator useful for producing a solution containing rhenium-188, comprising:
- disposing a substantially non-elutable inorganic layered hydroxide anion exchange composition into a container defining an eluant flow path;
- and
- exchanging tungstate anions onto the anion exchange composition.
A process for preparing a perrhenate solution, comprising:
- eluting perrhenate from a matrix consisting essentially of an insoluble inorganic layered hydroxide in the tungstate form.
Dependencies are inferred from the claim text.