US 7,323,546 B2 · Apoptosis-inducing polypeptides

Abstract

An isolated water-soluble VP1 polypeptide of foot-and-mouth disease virus and a nucleic acid encoding the polypeptide. Also disclosed are a pharmaceutical composition containing the polypeptide or nucleic acid and related methods of inducing apoptosis and treating an apoptosis-related disorder.

Claims6

Dependent claims

An isolated water-soluble polypeptide, wherein the polypeptide contains SEQ ID NO:

1 and, upon binding to a receptor on a cell, induces death of the cell.

Dependencies are inferred from the claim text.

Facts

Application

10/863,637Filed 8 Jun 2004 · continuation in part

Priority

29 May 2003

Published

US 2005/0058654 A117 Mar 2005

Granted

29 Jan 2008

Term ends

Not estimatedThe source records don’t support an estimate.

Classification18 codes

C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 31/7088
Carbohydrates; Sugars; Derivatives thereof: compounds having three or more nucleosides or nucleotides
A61K 38/162
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from virus
A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens

Family

Application10/449,531Parent of this continuation-in-part · filed 29 May 2003

US 2005/0058654 A1Pre-grant publication · published 17 Mar 2005

US 7,217,784 B2Parent of this continuation-in-part

US 2004/0242458 A1Published application

US 7,323,546 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

10/863,637Filed 8 Jun 2004 · continuation in part

Priority

29 May 2003

Published

US 2005/0058654 A117 Mar 2005

Granted

29 Jan 2008

Term ends

Not estimatedThe source records don’t support an estimate.

Classification18 codes

C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 31/7088
Carbohydrates; Sugars; Derivatives thereof: compounds having three or more nucleosides or nucleotides
A61K 38/162
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from virus
A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens

Family

Application10/449,531Parent of this continuation-in-part · filed 29 May 2003

US 2005/0058654 A1Pre-grant publication · published 17 Mar 2005

US 7,217,784 B2Parent of this continuation-in-part

US 2004/0242458 A1Published application

US 7,323,546 B2This patent

From the US filing history. Foreign family members aren’t listed.

Apoptosis-inducing polypeptides

Life of this patent

Abstract

Claims6

Apoptosis-inducing polypeptides

Life of this patent

Abstract

Claims6