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AssigneeDsm IP Assets B.V.
InventorsLuppo Edens, Albertus Van Dijk, Philipp Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang
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The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
A isolated polynucleotide that encodes a tripeptidyl peptidase wherein said polynucleotide hybridizes to the full length complement of SEQ ID NO:
An isolated polynucleotide encoding a tripeptidyl peptidase, which comprises a nucleotide sequence selected from the group consisting of SEQ ID NO:
An isolated polynucleotide encoding a polypeptide having tripeptidyl peptidase activity, said polypeptide comprising an amino acid sequence of SEQ ID NO:123;
An isolated polynucleotide encoding a polypeptide having tripeptidyl peptidase activity, which is at least 95% identical to SEQ ID NO:
An isolated polypeptide having tripeptidyl peptidase activity, which comprises an amino acid sequence selected from the group consisting of SEQ ID NO:123;
An isolated polypeptide having tripeptidyl peptidase activity, which comprises an amino acid sequence at least 95% identical to SEQ ID NO:
Dependencies are inferred from the claim text.