Liquid and low melting coatings for stents
Assigneeev3 Peripheral, Inc.
InventorChandrashekhar Pathak
Life of this patent
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Abstract
A method for forming liquid coatings for medical devices such as stents and angioplasty balloons is provided. The liquid coatings can be made from biodegradable materials in liquid, low melting solid, or wax forms, which preferably degrade in the body without producing potentially harmful fragments. The liquid coatings may also contain biologically active components, which are released from the coatings through diffusion from the coatings and the degradation of the coatings.
Claims23
A coated stent comprising a stent and a coating composition comprising a biologically active component and a nonpolymeric carrier component, the nonpolymeric carrier component selected from the group consisting of Vitamin E, Vitamin E acetate, Vitamin E succinate, oleic acid, peanut oil and cottonseed oil, and wherein the nonpolymeric carrier component has a melting point of about 50° C. or less and wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%.
A coated stent comprising a stent and a coating composition that includes a biologically active component and a nonpolymeric carrier, component wherein the nonpolymeric carrier component has a viscosity of from about 0.1 to about 15000 cP less and wherein the coating composition comprises a nonpolymeric carrier component by weight in the range from 50–99.9%.
A coated stent comprising a stent and a coating composition that includes a biologically active component and a nonpolymeric carrier, component, wherein the coating composition is in a solid state outside of a human body and melts to form a liquid inside of a human body.
A method of coating a stent comprising:
- providing a stent,
- providing a coating composition comprising a biologically active component and a nonpolymeric carrier component having a melting point of about 50° C. or less, and wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%;
- and
- applying the coating composition to the stent.
A method of coating a stent comprising:
- providing a stent,
- providing a coating composition comprising a biologically active component and a nonpolymeric carrier component having a viscosity of from about 0.1 to about 15000 cP, and, wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%;
- and
- applying the coating to the stent.
A method of treating restenosis comprising:
- deploying a coated stent into a body lumen of a patient, the coated stent comprising a stent and a coating composition comprising a biologically active component and a nonpolymeric carrier having a melting point of about 50° C. or less and wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%.
A method of treating restenosis comprising:
- deploying a coated stent into a body lumen of a patient, the coated stenting comprising a stent and a coating composition comprising a biologically active component and a nonpolymeric carrier component having a viscosity of from about 01. to about 15,000 cP and wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%.
A method of treating restenosis comprising:
- providing a coated stent comprising a stent, a biologically active component and a coating composition comprising a nonpolymeric carrier component and wherein the coating composition comprises the nonpolymeric carrier component by weight in the range from 50–99.9%;
- and
- deploying the coated stent into a body lumen of a patient, the coating composition changing from a solid to a liquid inside the patient.
A method of treating restenosis comprising:
- coupling a stent to a catheter,
- spraying the catheter and the stent with a coating composition comprising a biologically active component and a nonpolymeric carrier component having a melting point of about 50° C. or less, and
- deploying the coated stent into a body lumen of a patient.
Dependencies are inferred from the claim text.