Phytase-containing animal food and method
AssigneesPhytex, LLC, Cornell Research Foundation, Inc.
InventorsDouglas M. Webel, Donald E. Orr, Jr., Frank E. Ruch, Jr., Xingen Lei
Life of this patent
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Abstract
A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
Claims35
A method of improving the nutritional value of a foodstuff consumed by a monogastric animal by increasing the bioavailability of phosphate from phytate wherein the foodstuff comprises myo-inositol hexakisphosphate, the method comprising the step of feeding to the animal the foodstuff in combination with less than 1200 units of an E. coli 6-phytase expressed in yeast per kilogram of the foodstuff,
- wherein the bioavailability of phosphate from phytate is increased by at least 2-fold compared to the bioavailability of phosphate from phytate obtained by feeding the foodstuff in combination with the same units of a phytase expressed in a non-yeast host cell.
A method of improving the nutritional value of a foodstuff consumed by a monogastric animal wherein the foodstuff comprises myo-inositol hexakisphosphate, the method comprising the steps of:
- spray drying an E. coli 6-phytase;
- mixing the phytase with a carrier for the phytase and, optionally, other ingredients to produce a feed additive composition for supplementing the foodstuff with the phytase;
- mixing the feed additive composition with the foodstuff;
- and
- feeding the animal the foodstuff supplemented with the feed additive composition.
A method of improving the nutritional value of a foodstuff consumed by an avian species by increasing the bioavailability of phosphate from phytate wherein the foodstuff comprises myo-inositol hexaikisphosphate, the method comprising the step of feeding to the avian species the foodstuff in combination with less than 1200 units of an E. coli 6-phvtase expressed in yeast per kilogram of the foodstuff, wherein the bioavailability of phosphate from phytate is increased by at least 1.5-fold compared to the bioavailability of phosphate from phytate obtained by feeding to a non-avian species the foodstuff in combination with the phytase expressed in yeast.
Dependencies are inferred from the claim text.