Compositions and methods for eliciting immune or anti-infective responses
AssigneeBoard of Regents, The University of Texas System
InventorsJagannadha K. Sastry, Ralph B. Arlinghaus, Chris D. Platsoucas, Pramod N. Nehete
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Abstract
Disclosed are compositions and methods for the prevention and treatment of viral infections. The identification of distinct classes of peptides for use in both anti-viral vaccines and therapeutic formulations is reported. Peptide formulations are disclosed which enhance the systemic distribution, activity, and longevity of anti-viral cytotoxic T cells, and/or which protect human cells from HIV infection.
Claims14
A method for directly inhibiting HIV entry into a cell comprising the step of contacting said cell with an effective amount of a composition comprising a peptide of 8 to 24 residues comprising the sequence RAFVTIGK (SEQ ID NO:5), wherein said cell is in a human subject.
A method for directly inhibiting HIV entry into a cell in vitro comprising the step of contacting said cell with a composition comprising a peptide of 8 to 24 residues comprising the sequence RAFVTIGK (SEQ ID NO:5).
Dependencies are inferred from the claim text.