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US 7,312,361 B2Granted
Inhibitors of transthyretin amyloid fibril formation
AssigneeThe Scripps Research Institute
InventorsJeffery W. Kelly, Steven M. Johnson, H. Michael Petrassi
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Abstract
Bisaryloxime ethers and bisarylhydroazones are shown to be effective for inhibiting formation of amyloid fibrils of transthyretin.
Claims68
A bisarylhydrazone selected from the following structures:
A bisaryloxime ether selected from the following structures:
Dependencies are inferred from the claim text.