Membrane based volatile component-removal devices for liquid chromatography
AssigneeDionex Corporation
InventorsPurnendu K. Dasgupta, S. M. Rahmat Ullah, Kannan Srinivasan
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Abstract
In a liquid chromatographic system, removing at least part of a volatile component from the liquid sample stream after separation by flowing it through a volatile component-removal device including a porous wall having a surface coating of a permeable polymer less than 10 μm thick. A liquid chromatographic system suitable for performing the method. Also, a liquid chromatographic system in which volatile component is removed prior to separation across the same type of membrane or across a membrane made of a copolymer of perfluoro-2,2-dimethyl-1,3-dioxole.
Claims4
A liquid chromatographic system comprising:
- (a) a liquid chromatographic column having an inlet and an outlet,
- (b) a suppressor comprising a sample stream flow channel having an inlet and an outlet and separated by a permselective membrane from a regenerant stream flow channel having an inlet and an outlet, said liquid chromatographic column outlet in fluidic communication with the inlet of the said suppressor sample stream flow channel
- (c) a volatile component-removal device comprising a membrane comprising at least one porous wall, said device defining a liquid sample stream flow channel, having an inlet and an outlet, on one side of said membrane, and a receiving channel on the other side of said porous wall, said volatile component liquid sample stream flow channel inlet being in fluid communication with said suppressor sample stream outlet, and
- (d) said suppressor regenerant stream flow channel outlet being in fluid communication with said receiving channel of the volatile component-removal device.
Dependencies are inferred from the claim text.