InventorsMark E. Connell, Robert A. Bedient, Raymond Elsen, Michael E. Hogard, Harley D. Johnson, Thomas D. Kelly, Jean McEvoy Long, Bruce A. Peterson, William G. Preston, Jr., Dalibor J. Smejtek
A number of improvements relating to methods and apparatuses for kidney dialysis are disclosed. These include checking of dialysate bypass status using flow measurement; using a flow sensor to confirm the absence of ultrafiltration during bypass; automatic testing of ultrafiltration function by removal of a discrete volume from a portion of the dialysate flow path coupled with a pressure test of that part of the flow path; using a touch screen user interface; bar graph profile programming of ultrafiltration, sodium, and bicarbonate parameters; using a RAM card to upload treatment instructions to, and to download treatment data from, the machine; automatic setting of proportioning mode (acetate or bicarbonate) based on connections of concentrate lines; predicting dialysate conductivity values based on brand and formulation of concentrates; minimizing no-flow dead time between dialysate pulses; initiating operation in a timed mode from a machine power-off condition; preserving machine mode during machine power-fail condition; calibration scheduling and reminding; automatic level adjusting; and blood leak flow rate detecting.
Drawings
Claims19
A hemodialysis machine comprising:
at least one dialysate pump configured to move dialysate to a dialyzer;
a blood pump configured to move blood to the dialyzer;
and
a video screen and at least one processor configured to
(a) enter a total time and a cumulative ultrafiltration value,
(b) automatically calculate a constant ultrafiltration rate from the cumulative ultrafiltration value and the total time,
(c) display the constant rate on the video screen,
(d) enable a plurality of ultrafiltration values as steps over time forming an ultrafiltration profile to be entered thereafter via selection of a profile ultrafiltration option displayed on the video screen,
(e) use the constant calculated rate so that the cumulative ultrafiltration value is removed, through the dialyzer, within or over the total time, according to the constant rate, or
(f) display a shape of the ultrafiltration profile on the video screen and use the ultrafiltration profile alternatively so that thereafter the cumulative ultrafiltration value is removed, within or over the total time, according to the values as steps over time of the ultrafiltration profile.
7 more elements
A method of operating a dialysis machine including at least one dialysate pump configured to move dialysate to a dialyzer, a blood pump configured to move blood to the dialyzer, a video screen and at least one processor, the method comprising:
enabling a total time and a cumulative ultrafiltration value to be entered;
calculating a constant ultrafiltration rate by which the dialysis machine operates to remove the cumulative ultrafiltration value over the total time;
displaying the rate on the video screen;
displaying a profile ultrafiltration option on the video screen;
enabling a plurality of ultrafiltration values as steps over time forming an ultrafiltration profile to be entered thereafter via a selection of the profile ultrafiltration option;
removing the cumulative ultrafiltration value, through the dialyzer, within or over the total time, according to the constant ultrafiltration rate;
and
if the ultrafiltration profile is entered, displaying a shape of the ultrafiltration profile on the video screen and removing the cumulative ultrafiltration value, within or over the total time, alternatively according to the values as steps over time of the ultrafiltration profile.
19 Apr 2011Estimated · howhide20 years from earliest known nonprovisional domestic filing plus recorded patent term adjustment. Maintenance-fee lapses, terminal disclaimers and statutory extensions have not been checked. The continuity chain may be incomplete; this is not an enforceability determination.
Control or regulation: profiling or modelling of patient or predicted treatment evolution or outcome
Life of this patent
Term ended 19 Apr 2011 (estimated)
Priority19 Apr 1991
Filed13 Jun 2003
Published27 Nov 2003
Granted4 Dec 2007
Term ended19 Apr 2011
Priority19 Apr 1991
Granted4 Dec 2007
Term ended19 Apr 2011
Priority claimedParent application 07/688,174
Application filedUS 10/461,272
PublishedUS 2003/0217972 A1
Assigned to Althin Cd Medical, Inc.assignment of assignor's interest
Assigned to Althin Medical, Inc.change of name
Assigned to Baxter International Inc.assignment of assignor's interest
GrantedUS 7,303,680 B2
Term endedEstimated
Description18,862 words
Summary97 words
#The present invention relates to improvements in kidney dialysis machines.
#Kidney dialysis machines are well known in the art and are illustrated, for example, in U.S. Pat. Nos., 3,598,727, 4,172,033, 4,267,040, and 4,769,134.
#While machines according to the prior art provide a number of advantageous features, they nonetheless have certain limitations. The present invention seeks to overcome certain drawbacks of the prior art and to provide new features not heretofore available.
Brief description of the drawings11 figures
#FIGS. 1A and 1B show a schematic hydraulic diagram of a preferred embodiment of a kidney dialysis machine according to the present invention.
#FIG. 2 is a schematic diagram showing flow path locations and components of a pre-dialyzer flow sensor and a post-dialyzer, flow sensor according to the present invention.
#FIGS. 3A and 3B are isometric and schematic diagrams, respectively, of a concentrate-line proximity sensor comprising a portion of the automatic proportioning mode setting feature of the present invention.
Detailed description18,554 words
#A hydraulic circuit 10 representing a preferred embodiment of an improved hemodialysis machine according to the present invention is illustrated in FIGS. 1A and 1B. The hydraulic circuit 10 is comprised of the following principal components: an incoming water pressure regulator 12, a water on/off valve 14, a heat exchanger 16, a heater 18, a safety thermostat 20, an “A” concentrate pump 22, a supply valve 24, an air gap chamber 26, an “A” rinse fitting 28, a “B” rinse fitting 30, a deaeration sprayer 32, an air removal pump 34, a vented air trap 36, an “A” conductivity probe 38, a “B” concentrate pump 40, a supply pump 42, a “B” mix chamber 44, a “B” conductivity probe 46, a dialysate filter 48, a supply regulator 50, an input pressure equalizer 52, a flow equalizer 54, an output pressure equalizer 56, end-of-stroke sensors 58, 59, a dialysate conductivity probe 60, a pre-dialyzer flow sensor 62, a dialysate pressure transducer 64, a bypass valve 66, a dialysate sample port 68, a post-dialyzer flow sensor 70, a dialysate pressure pump 72, a UF removal regulator 74, a UF flow meter 76, a blood-leak detector 78, and a rinse valve 80. The aforementioned components are interconnected as shown in FIGS. 1A and 1B.
#The incoming water pressure regulator 12 is coupled to a pressurized water source 82 and reduces and stabilizes the water supply pressure to a level of about 20 psig.
#The water on/off valve 14 opens when machine power is on, thereby allowing water to flow from the source 82 into the hydraulic circuit 10. When the machine power is off, the water on/off valve 14 is closed.