Method and apparatus for detecting biomolecular interactions
AssigneeSRU Biosystems, Inc.
InventorsBrian T. Cunningham, Peter Y. Li, Frank DiFilippi
Life of this patent
Estimating the term…
Abstract
Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.
Claims7
A method of measuring biochemical surface interactions of a biosensor, said method comprising the steps of:
- incubating said biosensor at a predetermined temperature;
- providing a dual fiber optic probe with at least one illuminating fiber that is optically coupled to a light source, said illuminating fiber directing light towards a first surface of said biosensor;
- providing at least one detecting fiber, said at least one detecting fiber detecting light reflected from said first surface of the biosensor;
- optically coupling said at least one detecting fiber to a spectrometer;
- and
- analyzing said reflected light from said first surface of said biosensor.
Dependencies are inferred from the claim text.